Root Causes & Pillars
The 3 Collapsed Axes of the Body: Root Causes of Hair Loss
🛡️1. Immunity
LEEMOONWON’s View: Hair loss is not just hair falling out. Under stress and aging, the immune system becomes dysregulated and may start attacking self—your follicles included.
🔥2. Inflammation
LEEMOONWON’s View: Immune dysregulation fuels chronic scalp inflammation—an invisible ‘fire’ that keeps injuring follicular cells and turns the growth soil into a desert.
⚙️3. Regeneration
LEEMOONWON’s View: In this fire, cellular self-cleaning (autophagy) and the energy plants (mitochondria) stall. Cells lose the power to build new hair—leading to hair loss.
The HOW: Rebuilding with 4 Scientific Pillars
1. Epigenetics
Role: With LEEMOONWON formulas we turn off genes that drive immune chaos and inflammation, and turn on genes that support a healthy immune response—correcting the root malfunction.
2. Autophagy
Role: We activate the cell’s self-cleaning system to clear inflammatory “cellular debris”, restoring a clean environment for recovery.
3. Mitochondria
Role: We re-energize follicular mitochondria so cells can detox, repair, and power the building of new hair—restarting the stalled regeneration engine.
4. Microbiome
Role: We transform a pathogen-dominant, polluted scalp ecosystem into a fertile terrain rich in beneficial microbes—blocking inflammatory triggers and restoring the gut-to-hair nutrition axis.
Deep Dive into LEEMOONWON’s 4 Scientific Pillars
1. Epigenetics
Definition
Relevance to Hair Loss
Having “hair loss genes” doesn’t doom you. Chronic stress, poor diet, and sleep debt act as negative epigenetic switches—turning on genes that suppress follicle growth and drive inflammation, while turning off protective, pro-growth programs.
LEEMOONWON Approach
Our Body Re-Coding reverses those switches.
- Key actives: Ginsenosides (ginseng), baicalin (Scutellaria) help switch off harmful and switch on protective programs.
- Lifestyle coaching: Diet, sleep, and stress protocols help you keep your “super-hair genes” switched on in daily life.
Scientific Context
Epigenetic shifts are implicated across aging and chronic disease. Leading centers (e.g., Harvard, Stanford) actively research epigenetic modulation for prevention and therapy—an emerging medical paradigm.
2. Mitochondria
Definition
Relevance to Hair Loss
Building a hair fiber is energy-intensive. When function drops, hairs miniaturize and anagen shortens; ROS surge, accelerating follicle aging and inflammation.
LEEMOONWON Approach
- RF deep heat: 40–42 °C boosts mitochondrial metabolism up to ~4–5×.
- Key actives: CoQ10, PQQ, curcumin protect and optimize energy production.
- Network pharmacology: Personalized herbals improve circulation—oxygen & nutrients flow to follicles.
Scientific Context
Mitochondrial decline is a recognized hallmark of aging. Restoring function is central in longevity and functional medicine.
3. Autophagy
Definition
Relevance to Hair Loss
Debris build-up drives chronic inflammation and cell death, accelerating hair loss. When autophagy stalls, follicles suffocate in waste.
LEEMOONWON Approach
- EGCG & curcumin: Known to trigger autophagy switches.
- Lifestyle: Coaching can include intermittent-fasting principles to naturally enhance autophagy.
Scientific Context
Autophagy counters tumorigenesis, neurodegeneration, and aging—one of the most active research axes in longevity science.
4. Microbiome
Definition
Relevance to Hair Loss
The scalp is an ecosystem. When imbalanced, pathogens bloom, fueling seborrheic dermatitis and folliculitis. Gut dysbiosis (70% of immunity) heightens systemic inflammation and starves follicles of nutrients.
LEEMOONWON Approach
- Selective antimicrobials: Botanical actives suppress harmful microbes while supporting beneficials.
- Gut–brain–skin axis: Diet guidance and probiotics to rebuild the foundation.
- pH balance: Formulations support a mildly acidic scalp where pathogens struggle.
Scientific Context
Microbiome imbalance links to obesity, diabetes, atopy, depression, and more. Microbiome therapeutics are a rising frontier in pharma.